Metabolic engineering of crocins and picrocrocin apocarotenoids in potato group phureja, Gómez-Gómez, Lourdes, López-Jimenez Alberto José, Fajardo Cristian Martinez, Morote Lucía, Frusciante Sarah, Rambla Jose Luis, Diretto Gianfranco, Rubio-Moraga Ángela, Mondejar-López María, Niza Enrique, et al. , Engineering Reports, (2024)

Engineering the production of crocins and picrocrocin in heterologous plant systems, Gomez-Gomez, L., Morote L., Fajardo C.M., Rubio-Moraga A., Frusciante Sarah, Diretto Gianfranco, and Ahrazem O. , Industrial Crops and Products, Volume 194, (2023)

A new glycosyltransferase enzyme from family 91, ugt91p3, is responsible for the final glucosylation step of crocins in saffron (Crocus sativus l.), López, A.J., Frusciante Sarah, Niza E., Ahrazem O., Rubio-Moraga A., Diretto Gianfranco, and Gomez-Gomez L. , International Journal of Molecular Sciences, Volume 22, Number 16, (2021)

Efficient production of saffron crocins and picrocrocin in Nicotiana benthamiana using a virus-driven system, Martí, M., Diretto Gianfranco, Aragonés V., Frusciante Sarah, Ahrazem O., Gomez-Gomez L., and Daròs J.-A. , Metabolic Engineering, Volume 61, p.238-250, (2020)

Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants, Xu, Z., Xu Z., Pu X., Gao R., Demurtas Olivia Costantina, Fleck S.J., Richter M., He C., He C., Ji A., et al. , BMC Biology, Volume 18, Number 1, p.1–14, (2020)

ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas, Demurtas, Olivia Costantina, R. Francisco de Brito, Diretto Gianfranco, Ferrante Paola, Frusciante Sarah, Pietrella M., Aprea Giuseppe, Borghi L., Feeney M., Frigerio L., et al. , THE PLANT CELL, Volume 31, Number 11, p.2789–2804, (2019)

Candidate enzymes for saffron crocin biosynthesis are localized in multiple cellular compartments, Demurtas, Olivia Costantina, Frusciante Sarah, Ferrante Paola, Diretto Gianfranco, Azad N.H., Pietrella M., Aprea Giuseppe, Taddei A.R., Romano E., Mi J., et al. , Plant Physiology, Volume 177, Number 3, p.990-1006, (2018)

Transcriptome analysis in tissue sectors with contrasting crocins accumulation provides novel insights into apocarotenoid biosynthesis and regulation during chromoplast biogenesis, Ahrazem, O., Argandoña J., Fiore Alessia, Aguado C., Luján R., Rubio-Moraga A., Marro M., Araujo-Andrade C., Loza-Alvarez P., Diretto Gianfranco, et al. , Scientific Reports, Volume 8, Number 1, (2018)

Evolutionarily distinct carotenoid cleavage dioxygenases are responsible for crocetin production in Buddleja davidii, Ahrazem, O., Diretto Gianfranco, Argandoña J., Rubio-Moraga A., Julve J.M., Orzáez D., Granell A., and Gomez-Gomez L. , Journal of Experimental Botany, Volume 68, Number 16, p.4663-4677, (2017)

Unraveling massive crocins transport and accumulation through proteome and microscopy tools during the development of saffron stigma, Gomez-Gomez, L., Parra-Vega V., Rivas-Sendra A., Seguí-Simarro J.M., Molina R.V., Pallotti C., Rubio-Moraga A., Diretto Gianfranco, Prieto A., and Ahrazem O. , International Journal of Molecular Sciences, Volume 18, Number 1, (2017)

Novel carotenoid cleavage dioxygenase catalyzes the first dedicated step in saffron crocin biosynthesis, Frusciante, Sarah, Diretto Gianfranco, Bruno M., Ferrante Paola, Pietrella M., Prado-Cabrero A., Rubio-Moraga A., Beyer P., Gomez-Gomez L., Al-Babili S., et al. , Proceedings of the National Academy of Sciences of the United States of America, Volume 111, Number 33, p.12246-12251, (2014)